The two sides have made contrasting starts to their European campaigns this season as both were beaten in their first League Phase fixtures against Bayern Munich and Inter Milan respectively.
On the same night, Ajax were beaten 4-0 away at Marseille and arrive in west London still looking for their first points and goals in this season’s competition.
John Heitinga, who was part of Arne Slot’s coaching staff at Liverpool last season, has endured a difficult start to life as Ajax boss with speculation surrounding his future building amid a run of one win in five games.
While both teams are regulars in Europe’s premier competition, this will be just the third meeting between them and Chelsea will be seeking to maintain their unbeaten record.
Here’s everything you need to know about where to watch the match…
How to watch Chelsea vs Ajax
TV channel: In the UK, the game will be televised live on TNT Sports. Coverage starts at 7pm BST on TNT Sports 2 and TNT Sports Ultimate ahead of the 8pm kick-off.
Live stream: TNT Sports subscribers can also catch the contest live online via the Discovery+ app and website.
Live blog: You can follow all the action via Standard Sport’s live blog, with expert analysis from Dom Smith at the ground.