Both teams are without a point in Pool A, where they were always expected to be the whipping boys alongside Italy, New Zealand and France.
Namibia have never won a World Cup fixture in six previous trips to the competition, whereas Uruguay have at least avoided the wooden spoon in their pool on a number of occasions.
It was the South Americans who came out on top in this fixture only last month, as they faced off in a warm-up game that ended 26-18.
Having pushed France and Italy to a decent extent in their defeats so far, Uruguay are favourites to secure the victory today.
Where to watch Uruguay vs Namibia
TV channel: In the UK, this afternoon’s game will be shown live and free to air on ITV1, with coverage starting at 4pm BST ahead of a 4.45pm kick-off.
Live stream: Fans can also watch the match for free online via the ITV website and ITVX app.