Steve Borthwick’s men travelled up to Edinburgh after opening their campaign with an encouraging dismantling of Wales, but could not repeat the trick against their oldest rivals.
Henry Arundell was shown two yellow cards at Murrayfield, leaving England shorthanded for 30 of the 80 minutes as they plodded to a humbling defeat.
Today brings a presentable chance to get back to winning ways, though, as Ireland have also been less than perfect thus far in the competition.
They were on the wrong end of a lopsided scoreline as they visited the Stade de France to open their campaign, but bounced back last time out with a comeback defeat of Italy, which was not totally convincing.
The Azzurri led at the break, but could not convert their advantage in the second-half as Ireland edged back in front late on.
Both sides head to the Allianz Stadium, Twickenham, requiring a win, then, if they are to keep their fast dwindling hopes of winning the title alive.
How to watch England vs Ireland
TV channel: In the UK, England vs Ireland is being shown live and free to air on ITV1, with coverage beginning at 1pm GMT.
Live stream: Fans can also watch the game live online via the ITVX website and app, which is free with a registration.
Live blog: You can follow the action as it happens with Standard Sport’s dedicated live blog.